Across TCGA pan-cancer cohorts, YAP1P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of YAP1P1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where YAP1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types YAP1P1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

STAD, BRCA, and ESCA are the cancer types where YAP1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in YAP1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	II,III,IV	+0.159	.021	2	view →
BRCA	All	III,IV	−0.066	.030	2	view →
ESCA	Female	All	+0.280	.041	1	view →
LIHC	Female	III,IV	+0.028	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: YAP1P1 RNA expression & survival · all YAP1P1 data types