YAF2

Across TCGA patient cohorts, YAF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,111 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YAF2-associated proteins across cancer lineages are ARF6, MAPKAPK2, and SART3. Each is linked with YAF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both YAF2-to-partner and partner-to-YAF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YAF2 versus ARF6 in HNSC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YAF2→partner) and Y-score (partner→YAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARF6 →	-0.360	-0.330	.001	.001	3	4
BRCA	MAPKAPK2 →	+0.210	+0.276	<.001	<.001	3	4
LSCC	SART3 →	+0.217	+0.369	.002	.001	3	4
HNSC	HNRNPLL →	+0.277	+0.440	<.001	<.001	3	4
LSCC	SUGP2 →	+0.429	+0.404	<.001	<.001	3	4
GBM	ERO1A →	-0.546	-0.453	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,111 associations by consensus.

YAF2 vs ARF6 — HNSC

Explore this scatter interactively →