YAF2

Across TCGA cell cohorts, YAF2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,523 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible YAF2-associated genes across cancer lineages are KRTCAP3, HNF1B, and MRPL16. Each is linked with YAF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both YAF2-to-partner and partner-to-YAF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YAF2 versus KRTCAP3 in PANCREAS, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YAF2→partner) and Y-score (partner→YAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	KRTCAP3 →	+3.301	+1.701	<.001	.009	3	4
OVARY	HNF1B →	+3.311	+1.391	.002	.007	3	4
SOFT_TISSUE	MRPL16 →	-1.137	-1.547	.003	.001	3	4
LUNG_NSCLC_LUSC	ITM2B →	+2.053	+3.389	.001	.009	3	4
OVARY	INAVA →	+1.992	+1.183	.002	.002	3	4
OVARY	RPP14 →	-0.617	-1.808	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,523 associations by consensus.

YAF2 vs KRTCAP3 — PANCREAS

Explore this scatter interactively →