XYLT2

Across TCGA patient cohorts, XYLT2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,063 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XYLT2-associated genes across cancer lineages are MRPL27, SLC35B1, and STEAP4. Each is linked with XYLT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both XYLT2-to-partner and partner-to-XYLT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XYLT2 versus MRPL27 in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XYLT2→partner) and Y-score (partner→XYLT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPL27 →	+0.626	+0.554	.001	<.001	3	3
OV	SLC35B1 →	+0.371	+0.269	.003	.003	3	3
HNSC	STEAP4 →	-1.648	-0.360	<.001	<.001	3	3
COAD	LMO2 →	-0.911	-0.507	<.001	.005	3	3
COAD	ACKR1 →	-1.552	-0.502	<.001	.005	3	3
PDAC	IGKV2D-28 →	-1.819	-0.602	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,063 associations by consensus.

XYLT2 vs MRPL27 — BRCA

Explore this scatter interactively →