XYLT1

Across TCGA patient cohorts, XYLT1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,401 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible XYLT1-associated genes across cancer lineages are ADAM12, COL1A2, and CD248. Each is linked with XYLT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both XYLT1-to-partner and partner-to-XYLT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XYLT1 versus ADAM12 in OV, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XYLT1→partner) and Y-score (partner→XYLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADAM12 →	+2.252	+1.018	<.001	<.001	3	5
OV	COL1A2 →	+1.428	+0.613	<.001	<.001	3	5
OV	CD248 →	+1.475	+0.716	<.001	<.001	3	5
OV	VCAN →	+1.857	+0.654	<.001	<.001	3	5
OV	HEPH →	+1.501	+1.147	<.001	<.001	3	5
OV	FLT1 →	+1.108	+1.006	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,401 associations by consensus.

XYLT1 vs ADAM12 — OV

Explore this scatter interactively →