XXYLT1

Across TCGA cell cohorts, XXYLT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,015 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible XXYLT1-associated GO terms across cancer lineages are Mitotic chromosome condensation, Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery, and Negative regulation of cell cycle process. Each is linked with XXYLT1 in more than 11 cancer types. Because this analysis shows association rather than direction, both XXYLT1-to-partner and partner-to-XXYLT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by XXYLT1-low versus XXYLT1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XXYLT1→partner) and Y-score (partner→XXYLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitotic chromosome condensation →	+0.121	+1.149	<.001	<.001	3	12
OVARY	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.116	+0.952	.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.051	+0.935	.006	.001	2	12
LARGE_INTESTINE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.178	+0.823	<.001	<.001	3	11
LARGE_INTESTINE	Cell cycle phase transition →	+0.054	+0.691	<.001	<.001	3	11
OESOPHAGUS	Transcription initiation at RNA polymerase II promoter →	+0.064	+1.014	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,015 associations by consensus.

Mitotic chromosome condensation by XXYLT1 expression — BLOOD_Lymphoma

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