XRRA1

Across TCGA patient cohorts, XRRA1 mutation is significantly associated with the RNA expression of many other genes, with 3,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XRRA1-associated genes across cancer lineages are RNU6-520P, RNU6-847P, and RNA5SP325. Each is linked with XRRA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both XRRA1-to-partner and partner-to-XRRA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-520P grouped by XRRA1-low versus XRRA1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XRRA1→partner) and Y-score (partner→XRRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-520P →	+0.255	+3.458	.001	.003	3	2
SKCM	RNU6-847P →	+0.149	+5.163	<.001	.002	3	2
CESC	RNA5SP325 →	+0.158	+4.516	<.001	.004	3	2
HNSC	RNA5SP35 →	+0.286	+3.681	<.001	.005	3	2
LUSC	ATP5MFP6 →	+0.187	+4.561	.005	.005	3	2
LUAD	CELF2-DT →	+0.159	+4.631	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,150 associations by consensus.

RNU6-520P by XRRA1 expression — SKCM

Explore this box plot interactively →