XRRA1

Across TCGA cell cohorts, XRRA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,108 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible XRRA1-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and Protein exit from endoplasmic reticulum. Each is linked with XRRA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both XRRA1-to-partner and partner-to-XRRA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to cytosol transport grouped by XRRA1-low versus XRRA1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XRRA1→partner) and Y-score (partner→XRRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endoplasmic reticulum to cytosol transport →	+0.107	+1.008	.001	.005	1	10
STOMACH	Retrograde protein transport, ER to cytosol →	+0.107	+1.008	.001	.005	1	10
LUNG_SCLC	Protein exit from endoplasmic reticulum →	+0.109	+0.941	.002	<.001	3	8
OVARY	Response to starvation →	+0.036	+0.716	.009	.004	3	8
BLOOD_Lymphoma	Vacuole organization →	+0.032	+0.697	.001	<.001	2	8
SOFT_TISSUE	Positive regulation of microtubule nucleation →	+0.093	+0.483	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,108 associations by consensus.

Endoplasmic reticulum to cytosol transport by XRRA1 expression — STOMACH

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