XRCC6P4

Across TCGA patient cohorts, XRCC6P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,295 significant associations in total. STAD shows the largest number of these associations.

The most reproducible XRCC6P4-associated GO terms across cancer lineages are DNA replication, DNA-templated DNA replication, and DNA conformation change. Each is linked with XRCC6P4 in more than 18 cancer types. Because this analysis shows association rather than direction, both XRCC6P4-to-partner and partner-to-XRCC6P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by XRCC6P4-low versus XRCC6P4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC6P4→partner) and Y-score (partner→XRCC6P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA replication →	+0.056	+0.097	<.001	<.001	3	19
ESCA	DNA-templated DNA replication →	+0.073	+0.157	.004	.003	3	19
ESCA	DNA conformation change →	+0.074	+0.158	.002	.004	3	19
ESCA	Interstrand cross-link repair →	+0.064	+0.160	<.001	.001	3	19
STAD	Mitochondrial gene expression →	+0.054	+0.106	<.001	<.001	3	19
STAD	Regulation of mitochondrial gene expression →	+0.048	+0.103	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,295 associations by consensus.

DNA replication by XRCC6P4 expression — STAD

Explore this box plot interactively →