XRCC6P2

Across TCGA pan-cancer cohorts, XRCC6P2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated XRCC6P2 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher XRCC6P2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated XRCC6P2 expression acts as an unfavorable survival marker, although some lineages such as THCA and LUSC show a favorable association.

THCA, ACC, and LUSC are the cancer types where XRCC6P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Median	All	0.938	0.852	<.001	63	view →
ACC	DFS	Median	All	0.239	0.765	<.001	56	view →
LUSC	OS	Quartile	All	0.847	0.655	.001	51	view →
CESC	OS	Median	II,III,IV	0.878	0.639	.001	50	view →
READ	DFS	Tertile	All	0.940	0.716	.002	50	view →
SKCM	OS	Tertile	II,III,IV	0.947	0.724	<.001	33	view →
UVM	DFS	Quartile	III,IV	0.242	1.000	.010	27	view →
LIHC	DFS	Quartile	All	0.260	0.574	.002	27	view →
BRCA	DFS	Tertile	II,III,IV	0.435	0.583	.001	23	view →
MESO	OS	Median	All	0.457	0.643	.006	17	view →
KIRC	DFS	Median	III,IV	0.702	0.581	.012	15	view →
UCS	OS	Median	III,IV	0.423	0.734	.011	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

XRCC6P2–THCA (DFS)

Open the THCA breakdown →