XRCC6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, XRCC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,208 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible XRCC6-associated GO terms across cancer lineages are DNA replication, DNA-templated DNA replication, and Mitotic spindle midzone assembly. Each is linked with XRCC6 in more than 17 cancer types. Because this analysis shows association rather than direction, both XRCC6-to-partner and partner-to-XRCC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC6→partner) and Y-score (partner→XRCC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEDNA replication →+0.135+0.689.004.001318
BONEDNA-templated DNA replication →+0.169+0.740.001<.001318
KIDNEYMitotic spindle midzone assembly →+0.291+0.937<.001.002318
UPPER_AERODIGESTIVE_TRACTRegulation of chromosome condensation →+0.200+1.369<.001<.001318
KIDNEYMitotic spindle elongation →+0.291+0.937<.001.002318
BONEDNA replication initiation →+0.213+0.730.001.001317
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,208 associations by consensus.

Exploration