XRCC3

Across TCGA patient cohorts, XRCC3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XRCC3-associated genes across cancer lineages are Pericytes and B-cells. Each is linked with XRCC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both XRCC3-to-partner and partner-to-XRCC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by XRCC3-low versus XRCC3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC3→partner) and Y-score (partner→XRCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Pericytes →	+0.112	+4.173	<.001	.027	3	1
UCEC	B-cells →	+0.052	+2.158	<.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Pericytes by XRCC3 expression — BLCA

Explore this box plot interactively →