Across TCGA patient cohorts, XRCC2 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,141 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XRCC2-associated proteins across cancer lineages are XRCC3, YES1, and ZBED4_S624. Each is linked with XRCC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both XRCC2-to-partner and partner-to-XRCC2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC2→partner) and Y-score (partner→XRCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XRCC3 →	+0.970	+1.050	<.001	<.001	3	1
LSCC	YES1 →	+0.756	+1.111	.002	<.001	3	1
LSCC	ZBED4_S624 →	+0.905	+0.917	.002	.001	3	1
LSCC	ZC3H18_S67 →	+0.754	+1.062	<.001	<.001	3	1
LSCC	ZC3H4_S908 →	+1.994	+1.400	<.001	<.001	3	1
LSCC	ZC3HAV1L →	+0.915	+1.045	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,141 associations by consensus.

Exploration

XRCC2 survival (RNA) · tumor vs normal (RNA) · all XRCC2 data types