Across TCGA cell cohorts, XRCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,620 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible XRCC2-associated GO terms across cancer lineages are Regulation of G2/M transition of mitotic cell cycle, Regulation of cell cycle G2/M phase transition, and Replication fork processing. Each is linked with XRCC2 in more than 19 cancer types. Because this analysis shows association rather than direction, both XRCC2-to-partner and partner-to-XRCC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC2→partner) and Y-score (partner→XRCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of G2/M transition of mitotic cell cycle →	+0.079	+1.303	<.001	<.001	3	20
OESOPHAGUS	Regulation of cell cycle G2/M phase transition →	+0.070	+1.051	<.001	<.001	3	20
BONE	Replication fork processing →	+0.161	+2.084	<.001	<.001	3	20
BONE	Mitotic DNA replication checkpoint signaling →	+0.165	+1.140	<.001	<.001	3	20
PANCREAS	Interstrand cross-link repair →	+0.098	+1.607	<.001	<.001	3	20
STOMACH	Mitotic G2/M transition checkpoint →	+0.095	+1.128	<.001	.002	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,620 associations by consensus.

Exploration

XRCC2 survival (RNA) · tumor vs normal (RNA) · all XRCC2 data types