XPO7

Across TCGA pan-cancer cohorts, XPO7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated XPO7 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher XPO7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated XPO7 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and GBM are the cancer types where XPO7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	1.000	0.584	.025	8	view →
HNSC	OS	Tertile	II,III,IV	0.829	0.560	.004	7	view →
GBM	DFS	Tertile	All	0.182	0.418	.039	2	view →
CCRCC	DFS	Median	IV	0.382	0.932	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

XPO7–UCEC (OS)

Open the UCEC breakdown →