XPO7

Across TCGA patient cohorts, XPO7 protein abundance is significantly associated with the RNA expression of many other genes, with 4,964 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible XPO7-associated genes across cancer lineages are CCDC25, NEIL2, and CCAR2. Each is linked with XPO7 in more than 9 cancer types. Because this analysis shows association rather than direction, both XPO7-to-partner and partner-to-XPO7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XPO7 versus CCDC25 in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPO7→partner) and Y-score (partner→XPO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCDC25 →	+0.586	+0.290	<.001	<.001	3	10
UCEC	NEIL2 →	+0.760	+0.208	<.001	<.001	3	10
OV	CCAR2 →	+0.785	+0.426	<.001	<.001	3	10
OV	INTS9 →	+0.644	+0.299	.003	.005	3	9
OV	DCTN6 →	+0.689	+0.348	.001	<.001	3	9
OV	UBXN8 →	+0.837	+0.397	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,964 associations by consensus.

XPO7 vs CCDC25 — HNSC

Explore this scatter interactively →