XPO5

Across TCGA cell cohorts, XPO5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,660 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible XPO5-associated GO terms across cancer lineages are Recombinational repair, DNA replication initiation, and Maturation of LSU-rRNA. Each is linked with XPO5 in more than 18 cancer types. Because this analysis shows association rather than direction, both XPO5-to-partner and partner-to-XPO5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Recombinational repair grouped by XPO5-low versus XPO5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XPO5→partner) and Y-score (partner→XPO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Recombinational repair →	+0.089	+0.782	.002	.001	3	19
BONE	DNA replication initiation →	+0.185	+1.006	<.001	<.001	3	19
BONE	Maturation of LSU-rRNA →	+0.194	+1.222	<.001	<.001	3	17
BONE	DNA-templated transcription initiation →	+0.074	+0.935	.001	.001	3	17
OVARY	'de novo' IMP biosynthetic process →	+0.179	+0.724	<.001	<.001	3	17
BREAST	RNA export from nucleus →	+0.115	+0.829	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,660 associations by consensus.

Recombinational repair by XPO5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →