XPNPEP2

Across TCGA cell cohorts, XPNPEP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,093 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible XPNPEP2-associated GO terms across cancer lineages are NADP+ biosynthetic process, Detoxification of copper ion, and Positive regulation of cellular response to hypoxia. Each is linked with XPNPEP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both XPNPEP2-to-partner and partner-to-XPNPEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NADP+ biosynthetic process grouped by XPNPEP2-low versus XPNPEP2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XPNPEP2→partner) and Y-score (partner→XPNPEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NADP+ biosynthetic process →	+0.105	+0.303	<.001	.005	3	5
LARGE_INTESTINE	Detoxification of copper ion →	-0.287	-1.207	<.001	.001	3	4
LIVER	Positive regulation of cellular response to hypoxia →	+1.009	+0.668	.005	.005	3	4
LIVER	Negative regulation of cilium assembly →	-0.069	-0.634	<.001	.008	3	4
LARGE_INTESTINE	Stress response to copper ion →	-0.287	-1.207	<.001	.001	3	4
BONE	Antigen processing and presentation of peptide antigen via MHC class I →	-0.105	-0.676	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,093 associations by consensus.

NADP+ biosynthetic process by XPNPEP2 expression — BLOOD_Lymphoma

Explore this box plot interactively →