XPNPEP1

Across TCGA patient cohorts, XPNPEP1 RNA expression is significantly associated with the mutation status of many other genes, with 10,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XPNPEP1-associated genes across cancer lineages are TP53, IGSF10, and COL5A1. Each is linked with XPNPEP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both XPNPEP1-to-partner and partner-to-XPNPEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by XPNPEP1-low versus XPNPEP1-high in GBM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPNPEP1→partner) and Y-score (partner→XPNPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TP53 →	+1.584	+0.299	.003	<.001	3	6
STAD	IGSF10 →	+3.750	+0.430	<.001	.001	3	6
COAD	COL5A1 →	+1.846	+0.307	<.001	<.001	3	6
LUAD	HYDIN →	+1.549	+0.278	.008	.002	3	6
COAD	TENM3 →	+1.722	+0.389	<.001	<.001	3	6
CESC	ANK3 →	+2.817	+0.422	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,170 associations by consensus.

TP53 by XPNPEP1 expression — GBM

Explore this box plot interactively →