XPNPEP1

Across TCGA patient cohorts, XPNPEP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,065 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible XPNPEP1-associated genes across cancer lineages are ADD3, DPCD, and STN1. Each is linked with XPNPEP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both XPNPEP1-to-partner and partner-to-XPNPEP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XPNPEP1 versus ADD3 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XPNPEP1→partner) and Y-score (partner→XPNPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADD3 →	+0.745	+0.287	<.001	<.001	3	6
UCEC	DPCD →	+0.909	+0.233	.001	.001	3	6
UCEC	STN1 →	+0.485	+0.252	.001	<.001	3	5
UCEC	ECHS1 →	+1.105	+0.257	.006	.003	3	5
UCEC	PCBD1 →	+0.448	+0.271	<.001	<.001	3	5
COAD	ATP5MD →	+0.409	+0.176	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,065 associations by consensus.

XPNPEP1 vs ADD3 — UCEC

Explore this scatter interactively →