XKRYP6

Across TCGA patient cohorts, XKRYP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,080 significant associations in total. STAD shows the largest number of these associations.

The most reproducible XKRYP6-associated GO terms across cancer lineages are Negative regulation of phosphatase activity, Regulation of intracellular protein transport, and Positive regulation of MAP kinase activity. Each is linked with XKRYP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both XKRYP6-to-partner and partner-to-XKRYP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of phosphatase activity grouped by XKRYP6-low versus XKRYP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XKRYP6→partner) and Y-score (partner→XKRYP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of phosphatase activity →	+0.115	+0.006	<.001	.004	3	2
STAD	Regulation of intracellular protein transport →	+0.112	+0.010	<.001	.002	3	2
STAD	Positive regulation of MAP kinase activity →	+0.052	+0.008	.003	.005	3	2
STAD	Myoblast differentiation →	+0.100	+0.005	<.001	.001	3	2
STAD	Maintenance of protein location in nucleus →	+0.112	+0.005	<.001	.002	3	2
STAD	Protein K11-linked ubiquitination →	+0.113	+0.007	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,080 associations by consensus.

Negative regulation of phosphatase activity by XKRYP6 expression — STAD

Explore this box plot interactively →