XKRX

Across TCGA patient cohorts, XKRX RNA expression is significantly associated with the protein abundance of many other proteins, with 10,902 significant associations in total. GBM shows the largest number of these associations.

The most reproducible XKRX-associated proteins across cancer lineages are HUWE1, AKT3_S34, and GPSM2_S565. Each is linked with XKRX in more than 3 cancer types. Because this analysis shows association rather than direction, both XKRX-to-partner and partner-to-XKRX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XKRX versus HUWE1 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XKRX→partner) and Y-score (partner→XKRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HUWE1 →	+0.236	+0.549	<.001	.003	3	4
LSCC	AKT3_S34 →	-0.923	-1.208	<.001	<.001	3	4
LSCC	GPSM2_S565 →	+0.648	+0.752	.006	.006	3	4
LUAD	KRT80 →	+0.877	+1.671	<.001	<.001	3	4
UCEC	ZNF703 →	+0.587	+1.021	<.001	<.001	3	3
PDAC	PHACTR4_S557 →	+0.615	+0.459	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,902 associations by consensus.

XKRX vs HUWE1 — OV

Explore this scatter interactively →