XKRX

Across TCGA cell cohorts, XKRX RNA expression is significantly associated with the go_rna of many other GO terms, with 2,179 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible XKRX-associated GO terms across cancer lineages are Desmosome assembly, Regulation of myoblast fusion, and Cellular response to molecule of fungal origin. Each is linked with XKRX in more than 8 cancer types. Because this analysis shows association rather than direction, both XKRX-to-partner and partner-to-XKRX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Desmosome assembly grouped by XKRX-low versus XKRX-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XKRX→partner) and Y-score (partner→XKRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Desmosome assembly →	+0.237	+0.313	.001	.006	3	9
STOMACH	Regulation of myoblast fusion →	+0.114	+0.740	<.001	.008	3	9
OVARY	Cellular response to molecule of fungal origin →	+1.231	+0.387	<.001	<.001	3	8
BREAST	Response to indole-3-methanol →	+0.195	+0.502	<.001	<.001	3	8
OESOPHAGUS	Cellular response to indole-3-methanol →	+0.175	+0.586	.005	.004	3	8
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.064	+0.510	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,179 associations by consensus.

Desmosome assembly by XKRX expression — OVARY

Explore this box plot interactively →