Across TCGA patient cohorts, XKR9 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,544 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible XKR9-associated proteins across cancer lineages are LACTB2, PWWP2B_S206, and HDGF_S239. Each is linked with XKR9 in more than 4 cancer types. Because this analysis shows association rather than direction, both XKR9-to-partner and partner-to-XKR9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XKR9→partner) and Y-score (partner→XKR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LACTB2 →	+0.426	+1.146	<.001	<.001	3	5
GBM	PWWP2B_S206 →	-0.534	-0.456	.002	<.001	3	3
UCEC	HDGF_S239 →	+0.417	+0.661	<.001	.001	3	3
CCRCC	AHNAK_S5530 →	+0.712	+0.580	.002	.005	3	3
BRCA	F11R_S284 →	+0.693	+0.532	.007	.004	3	3
BRCA	ICAM1 →	+0.565	+0.526	.007	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,544 associations by consensus.

Exploration

XKR9 survival (RNA) · tumor vs normal (RNA) · all XKR9 data types