Across TCGA patient cohorts, XKR9 mutation is significantly associated with the RNA expression of many other genes, with 2,020 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XKR9-associated genes across cancer lineages are RPS29P13, H2AC16, and IZUMO3. Each is linked with XKR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both XKR9-to-partner and partner-to-XKR9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XKR9→partner) and Y-score (partner→XKR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RPS29P13 →	+0.249	+7.977	<.001	.007	3	2
UCEC	H2AC16 →	+0.527	+2.847	.003	.001	3	2
COAD	IZUMO3 →	+0.309	+5.122	<.001	.004	3	2
COAD	SS18L2P1 →	+1.057	+4.543	<.001	.005	3	2
COAD	PTP4A1P2 →	+0.473	+4.295	<.001	.008	3	2
HNSC	RPSAP35 →	+0.070	+5.303	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,020 associations by consensus.

Exploration

XKR9 survival (RNA) · tumor vs normal (RNA) · all XKR9 data types