Across TCGA cell cohorts, XKR9 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible XKR9-associated genes across cancer lineages are TNP1, H1-8, and OR8K3. Each is linked with XKR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both XKR9-to-partner and partner-to-XKR9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XKR9→partner) and Y-score (partner→XKR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TNP1 →	+0.341	+4.981	<.001	.008	3	1
CNS	H1-8 →	+0.030	+6.357	<.001	<.001	3	1
CNS	OR8K3 →	+0.006	+5.754	.002	.002	3	1
SKIN	CLEC10A →	+0.028	+4.273	.001	.006	3	1
SKIN	CARTPT →	+0.032	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR9K2 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

XKR9 survival (RNA) · tumor vs normal (RNA) · all XKR9 data types