XKR7

Across TCGA patient cohorts, XKR7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,435 significant associations in total. GBM shows the largest number of these associations.

The most reproducible XKR7-associated proteins across cancer lineages are PPFIA3_S683, SYP, and CNKSR2_S390. Each is linked with XKR7 in more than 3 cancer types. Because this analysis shows association rather than direction, both XKR7-to-partner and partner-to-XKR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XKR7 versus PPFIA3_S683 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XKR7→partner) and Y-score (partner→XKR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPFIA3_S683 →	+0.673	+0.575	<.001	<.001	3	4
GBM	SYP →	+1.144	+0.526	<.001	<.001	3	3
LSCC	CNKSR2_S390 →	+1.046	+0.159	.002	.002	3	3
LSCC	CRMP1_T509 →	+0.789	+0.260	.001	.007	3	3
GBM	GPRIN1_S615 →	+1.155	+0.666	<.001	<.001	3	3
PDAC	RTN1 →	+0.408	+0.218	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,435 associations by consensus.

XKR7 vs PPFIA3_S683 — GBM

Explore this scatter interactively →