XKR7

Across TCGA patient cohorts, XKR7 protein abundance is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. GBM shows the largest number of these associations.

The most reproducible XKR7-associated genes across cancer lineages are ANTKMT, BNIP3L, and SPATA6L. Each is linked with XKR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both XKR7-to-partner and partner-to-XKR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XKR7 versus ANTKMT in GBM, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XKR7→partner) and Y-score (partner→XKR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ANTKMT →	-0.752	-0.621	<.001	.005	3	1
GBM	BNIP3L →	+0.825	+0.578	.001	.002	3	1
GBM	SPATA6L →	-0.561	-0.645	.007	.003	3	1
GBM	NUTM2F →	-0.543	-0.547	.007	.001	3	1
GBM	KRT85 →	-0.101	-0.670	.005	.002	3	1
GBM	GLYR1 →	-0.239	-0.462	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

XKR7 vs ANTKMT — GBM

Explore this scatter interactively →