XKR5

Across TCGA patient cohorts, XKR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,490 significant associations in total. GBM shows the largest number of these associations.

The most reproducible XKR5-associated proteins across cancer lineages are SASH3, SMARCA1, and BLNK. Each is linked with XKR5 in more than 4 cancer types. Because this analysis shows association rather than direction, both XKR5-to-partner and partner-to-XKR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XKR5 versus SASH3 in GBM, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XKR5→partner) and Y-score (partner→XKR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SASH3 →	-0.424	-0.487	<.001	<.001	3	5
HNSC	SMARCA1 →	+0.605	+0.547	<.001	<.001	3	5
LSCC	BLNK →	-0.523	-0.515	<.001	.001	3	5
GBM	VSIR_S235 →	-0.797	-0.758	<.001	<.001	3	4
GBM	RGS10 →	-0.516	-0.471	<.001	<.001	3	4
GBM	WAS →	-0.560	-0.535	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,490 associations by consensus.

XKR5 vs SASH3 — GBM

Explore this scatter interactively →