XK

Across TCGA cell cohorts, XK RNA expression is significantly associated with the go_rna of many other GO terms, with 2,921 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible XK-associated GO terms across cancer lineages are Dentinogenesis, Lipoxygenase pathway, and ER-nucleus signaling pathway. Each is linked with XK in more than 6 cancer types. Because this analysis shows association rather than direction, both XK-to-partner and partner-to-XK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dentinogenesis grouped by XK-low versus XK-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XK→partner) and Y-score (partner→XK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Dentinogenesis →	-1.064	-0.897	.008	.001	3	7
LUNG_NSCLC_LUAD	Lipoxygenase pathway →	-0.180	-0.902	.007	.005	3	7
OVARY	ER-nucleus signaling pathway →	+0.100	+0.974	<.001	.004	3	7
PANCREAS	Establishment or maintenance of monopolar cell polarity →	-0.128	-1.117	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Lymphocyte aggregation →	-0.531	-0.839	.006	.005	3	6
LIVER	Negative regulation of activated T cell proliferation →	+0.263	+1.447	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,921 associations by consensus.

Dentinogenesis by XK expression — OVARY

Explore this box plot interactively →