XIRP2

Across TCGA patient cohorts, XIRP2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,914 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible XIRP2-associated genes across cancer lineages are ENHO, HCAR3, and MIR762HG. Each is linked with XIRP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both XIRP2-to-partner and partner-to-XIRP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XIRP2 versus ENHO in OV, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XIRP2→partner) and Y-score (partner→XIRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ENHO →	-1.966	-0.641	.007	.008	3	2
PDAC	HCAR3 →	+0.725	+1.662	<.001	<.001	3	2
OV	MIR762HG →	-0.601	-0.641	.008	.008	3	2
HNSC	IFFO1 →	+0.455	+0.751	<.001	<.001	3	2
LSCC	MEST →	-0.607	-0.531	.003	.008	3	2
HNSC	CXCL12 →	+0.977	+1.041	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,914 associations by consensus.

XIRP2 vs ENHO — OV

Explore this scatter interactively →