XIRP2

Across TCGA cell cohorts, XIRP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,240 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible XIRP2-associated GO terms across cancer lineages are Renal tubular secretion, Positive regulation of nitric-oxide synthase activity, and Synaptic transmission, glycinergic. Each is linked with XIRP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both XIRP2-to-partner and partner-to-XIRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal tubular secretion grouped by XIRP2-low versus XIRP2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XIRP2→partner) and Y-score (partner→XIRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Renal tubular secretion →	-0.559	-0.043	.002	.009	2	5
BREAST	Positive regulation of nitric-oxide synthase activity →	-1.323	-0.026	<.001	.003	3	4
BREAST	Synaptic transmission, glycinergic →	+1.186	+0.026	<.001	.004	3	4
BREAST	White fat cell proliferation →	-1.081	-0.020	<.001	.002	3	4
SOFT_TISSUE	Actin filament fragmentation →	+0.116	+1.206	<.001	.005	3	4
BREAST	Positive regulation of excitatory synapse assembly →	-0.836	-0.019	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,240 associations by consensus.

Renal tubular secretion by XIRP2 expression — URINARY_TRACT

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