Across TCGA patient cohorts, WWP2 mutation is significantly associated with the RNA expression of many other genes, with 1,468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WWP2-associated genes across cancer lineages are BAK1, GCH1, and OSTF1. Each is linked with WWP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both WWP2-to-partner and partner-to-WWP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WWP2→partner) and Y-score (partner→WWP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BAK1 →	+0.539	+2.595	.001	.006	3	3
UCEC	GCH1 →	+0.464	+1.547	.002	.004	3	3
UCEC	OSTF1 →	+0.395	+2.711	<.001	.003	3	3
UCEC	CCNA2 →	+0.557	+1.906	.002	.001	3	3
SKCM	ELAVL4-AS1 →	+0.092	+2.047	.008	.002	3	2
CESC	RN7SKP258 →	+0.125	+4.144	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,468 associations by consensus.

Exploration

WWP2 survival (RNA) · tumor vs normal (RNA) · all WWP2 data types