Across TCGA cell cohorts, WWP2 mutation is significantly associated with the RNA expression of many other genes, with 399 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WWP2-associated genes across cancer lineages are SNU13, NKX2-6, and SCRT2. Each is linked with WWP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WWP2-to-partner and partner-to-WWP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WWP2→partner) and Y-score (partner→WWP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNU13 →	+0.452	+3.212	.008	.006	3	2
LUNG_NSCLC_LUAD	NKX2-6 →	+0.693	+2.959	<.001	.004	3	2
SKIN	SCRT2 →	+0.006	+4.095	<.001	.009	3	1
BLOOD_Leukemia	WFDC11 →	+0.030	+4.539	<.001	.007	3	1
BLOOD_Leukemia	REC114 →	+0.101	+4.409	<.001	.005	3	1
BLOOD_Leukemia	TSSK1B →	+0.019	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 399 associations by consensus.

Exploration

WWP2 survival (RNA) · tumor vs normal (RNA) · all WWP2 data types