WWP1P1

Across TCGA pan-cancer cohorts, WWP1P1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated WWP1P1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher WWP1P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WWP1P1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

UVM, KIRC, and LGG are the cancer types where WWP1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.436	0.759	.001	84	view →
KIRC	DFS	Tertile	All	0.699	0.506	.001	35	view →
LGG	DFS	Tertile	All	0.723	0.865	<.001	32	view →
STAD	DFS	Median	All	0.481	0.618	.003	26	view →
ACC	DFS	Quartile	II,III,IV	0.123	0.584	.003	25	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	21	view →
BRCA	OS	Quartile	III,IV	0.956	0.845	.009	18	view →
COAD	DFS	Tertile	IV	0.343	0.587	.013	18	view →
KICH	OS	Median	II,III,IV	0.876	1.000	.016	13	view →
CHOL	OS	Quartile	All	0.206	0.848	.017	6	view →
UCS	DFS	Median	IV	0.886	0.443	.031	6	view →
LUAD	OS	Median	All	0.179	0.457	.016	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

WWP1P1–UVM (OS)

Open the UVM breakdown →