WWP1

Across TCGA cell cohorts, WWP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,629 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WWP1-associated GO terms across cancer lineages are Vesicle-mediated transport between endosomal compartments, Early endosome to late endosome transport, and Anterograde dendritic transport of messenger ribonucleoprotein complex. Each is linked with WWP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both WWP1-to-partner and partner-to-WWP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport between endosomal compartments grouped by WWP1-low versus WWP1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WWP1→partner) and Y-score (partner→WWP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vesicle-mediated transport between endosomal compartments →	+0.070	+1.020	.006	.006	2	13
STOMACH	Early endosome to late endosome transport →	+0.070	+1.020	.006	.006	2	13
STOMACH	Anterograde dendritic transport of messenger ribonucleoprotein complex →	+0.160	+1.219	.005	.003	3	11
BLOOD_Lymphoma	Endosomal transport →	+0.041	+0.971	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Double-strand break repair via alternative nonhomologous end joining →	+0.086	+0.655	.003	.001	3	10
LUNG_SCLC	Golgi organization →	+0.054	+0.664	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,629 associations by consensus.

Vesicle-mediated transport between endosomal compartments by WWP1 expression — STOMACH

Explore this box plot interactively →