WWC3

Across TCGA patient cohorts, WWC3 RNA expression is significantly associated with the RNA expression of many other genes, with 19,879 significant associations in total. THYM shows the largest number of these associations.

The most reproducible WWC3-associated genes across cancer lineages are GPATCH8, TCF20, and CHD8. Each is linked with WWC3 in more than 33 cancer types. Because this analysis shows association rather than direction, both WWC3-to-partner and partner-to-WWC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWC3 versus GPATCH8 in ACC, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WWC3→partner) and Y-score (partner→WWC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	GPATCH8 →	+1.210	+1.213	<.001	<.001	3	34
UCS	TCF20 →	+0.908	+0.837	<.001	<.001	3	33
ACC	CHD8 →	+1.165	+1.116	<.001	<.001	3	33
THYM	STAG1 →	+1.284	+1.104	<.001	<.001	3	33
CHOL	MED13L →	+1.017	+1.908	<.001	<.001	3	33
THYM	PPFIA1 →	+1.043	+1.209	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,879 associations by consensus.

WWC3 vs GPATCH8 — ACC

Explore this scatter interactively →