WWC3

Across TCGA patient cohorts, WWC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,738 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WWC3-associated proteins across cancer lineages are WWC3_S927, FERMT2, and FSTL1. Each is linked with WWC3 in more than 8 cancer types. Because this analysis shows association rather than direction, both WWC3-to-partner and partner-to-WWC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWC3 versus WWC3_S927 in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WWC3→partner) and Y-score (partner→WWC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WWC3_S927 →	+0.778	+0.879	.003	.001	3	9
UCEC	FERMT2 →	+0.610	+0.402	<.001	.004	3	6
BRCA	FSTL1 →	+0.616	+0.581	<.001	<.001	3	6
BRCA	WWC3_S957 →	+1.038	+1.170	.002	.008	3	6
OV	VCAN →	+0.854	+0.597	<.001	<.001	3	5
HNSC	VCL_S346 →	+0.587	+0.853	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,738 associations by consensus.

WWC3 vs WWC3_S927 — BRCA

Explore this scatter interactively →