WSB1

Across TCGA patient cohorts, WSB1 mutation is significantly associated with the RNA expression of many other genes, with 2,652 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WSB1-associated genes across cancer lineages are RNU2-15P, MIR4705, and MIR383. Each is linked with WSB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both WSB1-to-partner and partner-to-WSB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-15P grouped by WSB1-low versus WSB1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WSB1→partner) and Y-score (partner→WSB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU2-15P →	+0.236	+3.621	<.001	.001	3	3
SKCM	MIR4705 →	+0.311	+7.816	<.001	.008	3	3
STAD	MIR383 →	+0.530	+3.745	<.001	.001	3	2
STAD	RNU2-43P →	+0.385	+3.553	<.001	.001	3	2
LIHC	OR5A1 →	+0.034	+4.647	<.001	.007	3	2
LIHC	SMSP1 →	+0.033	+5.149	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,652 associations by consensus.

RNU2-15P by WSB1 expression — STAD

Explore this box plot interactively →