WRNIP1

Across TCGA pan-cancer cohorts, WRNIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WRNIP1 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher WRNIP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated WRNIP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, CCRCC, and HNSC are the cancer types where WRNIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.966	0.667	.003	37	view →
CCRCC	DFS	Quartile	III,IV	0.905	0.414	.005	18	view →
HNSC	OS	Median	III,IV	0.484	1.000	.038	10	view →
GBM	OS	Median	All	0.553	0.258	<.001	9	view →
UCEC	OS	Median	All	0.909	0.990	.035	2	view →
LUAD	DFS	Tertile	All	0.769	0.451	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WRNIP1–LSCC (OS)

Open the LSCC breakdown →