WRNIP1

Across TCGA patient cohorts, WRNIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WRNIP1-associated genes across cancer lineages are RIOK1, BPHL, and PSMG4. Each is linked with WRNIP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both WRNIP1-to-partner and partner-to-WRNIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WRNIP1 versus RIOK1 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WRNIP1→partner) and Y-score (partner→WRNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RIOK1 →	+0.851	+0.329	<.001	<.001	3	9
OV	BPHL →	+0.690	+0.649	<.001	<.001	3	9
HNSC	PSMG4 →	+0.779	+0.488	<.001	<.001	3	9
HNSC	PRPF4B →	+0.703	+0.296	<.001	<.001	3	8
OV	SIRT5 →	+0.823	+0.652	<.001	<.001	3	8
LSCC	NUP153 →	+0.635	+0.400	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,148 associations by consensus.

WRNIP1 vs RIOK1 — HNSC

Explore this scatter interactively →