WRNIP1

Across TCGA patient cohorts, WRNIP1 mutation is significantly associated with the RNA expression of many other genes, with 3,270 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WRNIP1-associated genes across cancer lineages are RNA5SP26, TRGJP, and CYCSP44. Each is linked with WRNIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both WRNIP1-to-partner and partner-to-WRNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP26 grouped by WRNIP1-low versus WRNIP1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WRNIP1→partner) and Y-score (partner→WRNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP26 →	+0.317	+8.055	<.001	.007	3	2
CESC	TRGJP →	+0.540	+4.384	<.001	.008	3	2
SKCM	CYCSP44 →	+0.224	+3.182	<.001	.006	3	2
BRCA	MIR6879 →	+0.500	+8.055	<.001	.007	3	1
UCEC	RDM1 →	+0.473	+1.874	.001	.002	3	1
UCEC	MYO19 →	+0.554	+3.058	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,270 associations by consensus.

RNA5SP26 by WRNIP1 expression — BRCA

Explore this box plot interactively →