WRNIP1

Across TCGA cell cohorts, WRNIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,735 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WRNIP1-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Regulation of peptidyl-lysine crotonylation, and Negative regulation of peptidyl-lysine crotonylation. Each is linked with WRNIP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both WRNIP1-to-partner and partner-to-WRNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by WRNIP1-low versus WRNIP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WRNIP1→partner) and Y-score (partner→WRNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of RNA export from nucleus →	+0.130	+0.733	<.001	.004	2	15
OVARY	Regulation of peptidyl-lysine crotonylation →	+0.124	+0.618	<.001	.001	2	11
OVARY	Negative regulation of peptidyl-lysine crotonylation →	+0.124	+0.618	<.001	.001	2	11
PANCREAS	Proteasome core complex assembly →	+0.182	+0.713	<.001	<.001	3	9
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.096	+0.558	<.001	.001	3	9
KIDNEY	Regulation of mitotic metaphase/anaphase transition →	+0.100	+0.558	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,735 associations by consensus.

Negative regulation of RNA export from nucleus by WRNIP1 expression — OVARY

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