WNT9B

Across TCGA pan-cancer cohorts, WNT9B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated WNT9B data layer compared with 25 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher WNT9B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated WNT9B expression acts as an unfavorable survival marker.

LIHC, COAD, and SKCM are the cancer types where WNT9B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.173	0.688	.041	6	view →
COAD	DFS	Median	All	0.485	0.794	.018	3	view →
SKCM	DFS	Median	III,IV	0.087	0.647	.013	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

WNT9B–LIHC (OS)

Open the LIHC breakdown →