WNT9B

Across TCGA patient cohorts, WNT9B mutation is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible WNT9B-associated genes across cancer lineages are RPL22P14, MIR4286, and RNA5SP458. Each is linked with WNT9B in more than 2 cancer types. Because this analysis shows association rather than direction, both WNT9B-to-partner and partner-to-WNT9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL22P14 grouped by WNT9B-low versus WNT9B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT9B→partner) and Y-score (partner→WNT9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL22P14 →	+0.195	+3.496	<.001	.008	3	3
UCS	MIR4286 →	+0.513	+5.087	<.001	.006	3	2
BLCA	RNA5SP458 →	+0.344	+4.788	.004	.006	3	2
SKCM	MIR1205 →	+0.345	+2.393	.002	.009	3	2
UCS	OR6C2 →	+0.199	+5.700	<.001	.002	3	1
UCS	SNORA10B →	+0.556	+5.087	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

RPL22P14 by WNT9B expression — COAD

Explore this box plot interactively →