WNT9B

Across TCGA cell cohorts, WNT9B RNA expression is significantly associated with the go_rna of many other GO terms, with 443 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WNT9B-associated GO terms across cancer lineages are Epithelial to mesenchymal transition involved in endocardial cushion formation, Positive regulation of endosome organization, and Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Each is linked with WNT9B in more than 2 cancer types. Because this analysis shows association rather than direction, both WNT9B-to-partner and partner-to-WNT9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial to mesenchymal transition involved in endocardial cushion formation grouped by WNT9B-low versus WNT9B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT9B→partner) and Y-score (partner→WNT9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Epithelial to mesenchymal transition involved in endocardial cushion formation →	-0.443	-0.019	<.001	.008	3	3
LUNG_SCLC	Positive regulation of endosome organization →	+0.067	+0.086	.003	.002	3	3
LARGE_INTESTINE	Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.091	+0.013	<.001	.006	3	2
LARGE_INTESTINE	Positive regulation of potassium ion import across plasma membrane →	-0.143	-0.019	.005	.008	3	2
LARGE_INTESTINE	Triglyceride-rich lipoprotein particle remodeling →	+1.237	+0.013	<.001	.006	3	2
LARGE_INTESTINE	Very-low-density lipoprotein particle remodeling →	+1.078	+0.013	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 443 associations by consensus.

Epithelial to mesenchymal transition involved in endocardial cushion formation by WNT9B expression — LARGE_INTESTINE

Explore this box plot interactively →