WNT9A

Across TCGA pan-cancer cohorts, WNT9A mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of WNT9A’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where WNT9A mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types WNT9A is over-expressed in tumor, although a few such as COAD and LSCC show the opposite, repressed pattern.

COAD, LSCC, and LUAD are the cancer types where WNT9A tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WNT9A mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−1.023	.004	6	view →
LSCC	All	All	−0.398	.004	4	view →
LUAD	Female	All	−0.600	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

WNT9A–COAD

Open the COAD breakdown →