WNT8B

Across TCGA patient cohorts, WNT8B protein abundance is significantly associated with the RNA expression of many other genes, with 5,684 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WNT8B-associated genes across cancer lineages are EDN2, PIK3IP1, and KCNA7. Each is linked with WNT8B in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT8B-to-partner and partner-to-WNT8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT8B versus EDN2 in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT8B→partner) and Y-score (partner→WNT8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EDN2 →	+1.488	+1.303	.001	.003	3	2
BRCA	PIK3IP1 →	-0.713	-1.271	.004	.005	3	1
BRCA	KCNA7 →	+0.043	+1.263	.009	.005	3	1
BRCA	MEST →	+1.269	+1.431	.003	.001	3	1
BRCA	MAP2K6 →	+0.706	+1.300	.001	.004	3	1
BRCA	PEX7 →	-1.066	-1.613	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,684 associations by consensus.

WNT8B vs EDN2 — BRCA

Explore this scatter interactively →