WNT6

Across TCGA patient cohorts, WNT6 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,084 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible WNT6-associated proteins across cancer lineages are LAMTOR4, ANP32A, and MIER1_S166. Each is linked with WNT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT6-to-partner and partner-to-WNT6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT6 versus LAMTOR4 in BRCA, with a Pearson correlation of -0.91.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT6→partner) and Y-score (partner→WNT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LAMTOR4 →	-0.731	-1.305	.006	<.001	3	1
BRCA	ANP32A →	-0.705	-1.439	.002	<.001	3	1
BRCA	MIER1_S166 →	-1.060	-1.304	.008	<.001	3	1
BRCA	MLPH_S564 →	-1.175	-1.305	.004	<.001	3	1
BRCA	NCOR1_S1496 →	-0.605	-1.305	<.001	<.001	3	1
BRCA	OSBPL3_S251 →	-1.105	-1.485	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,084 associations by consensus.

WNT6 vs LAMTOR4 — BRCA

Explore this scatter interactively →