WNT2B

Across TCGA cell cohorts, WNT2B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,477 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WNT2B-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Viral translational termination-reinitiation. Each is linked with WNT2B in more than 11 cancer types. Because this analysis shows association rather than direction, both WNT2B-to-partner and partner-to-WNT2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by WNT2B-low versus WNT2B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT2B→partner) and Y-score (partner→WNT2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.123	+0.977	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.109	+0.815	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.087	+0.670	.002	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to nucleus →	+0.101	+1.058	.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.076	+0.893	<.001	.001	3	11
BONE	Establishment of protein localization to plasma membrane →	+0.107	+0.831	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,477 associations by consensus.

Negative regulation of myoblast fusion by WNT2B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →